منابع مشابه
Social-cognitive deficits in normal aging.
A sizeable number of studies have implicated the default network (e.g., medial prefrontal and parietal cortices) in tasks that require participants to infer the mental states of others (i.e., to mentalize). Parallel research has demonstrated that default network function declines over the lifespan, suggesting that older adults may show impairments in social-cognitive tasks that require mentaliz...
متن کاملCognitive Deficits, Changes in Synaptic Function, and Brain Pathology in a Mouse Model of Normal Aging
Age is the main risk factor for sporadic Alzheimer’s disease. Yet, cognitive decline in aged rodents has been less well studied, possibly due to concomitant changes in sensory or locomotor function that can complicate cognitive tests. We tested mice that were 3, 11, and 23 months old in cognitive, sensory, and motor measures, and postmortem measures of gliosis and neural activity (c-Fos). Hippo...
متن کاملCognitive Decline in Patients with Chronic Hydrocephalus and Normal Aging: ‘Growing into Deficits’
BACKGROUND/AIM To explore the theory of 'growing into deficits', a concept known from developmental neurology, in a series of cases with chronic hydrocephalus (CH). METHODS Patients were selected from the Amsterdam Dementia Cohort and underwent extensive dementia screening. RESULTS Twelve patients with CH were selected, in whom Alzheimer's disease was considered unlikely, based on biomarker...
متن کاملMotor and cognitive changes in normal aging
In a recent study, Cid-Fernandez et al. (2014) tested attentional performance in 3 age groups: young (21–29 years old), middle-aged (51–64 years old), and older adults (65–84 years old). The task used in this study involved presenting both visual and auditory cues to the participants, and they were required to pay attention to the visual cues while ignoring the auditory cues (for task details, ...
متن کاملCognitive plasticity in normal and pathological aging
The main goal of the present study is to examine to what extent age and cognitive impairment contribute to learning performance (cognitive plasticity, cognitive modifiability, or learning potential). To address this question, participants coming from four studies (Longitudinal Study of Active Aging, age range, 55-75 years, N = 458; Longitudinal Study in the very old [90+], age range, 90-102, N ...
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ژورنال
عنوان ژورنال: Journal of Neuroscience
سال: 2012
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.5511-11.2012